Thermo Fisher Scientific Cytokeratin 19 Monoclonal Antibody (ZY418)
Human reactive monoclonal antibody (clone ZY418) targeting Cytokeratin 19; suitable for WB and IHC-P applications. Unconjugated, Protein A purified, 0.5 mg/mL concentration. Useful for epithelial tumor differentiation and breast carcinoma detection res...
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC-P)
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZY418 |
| Immunogen | A synthetic peptide corresponding to the C-terminus of CK19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Breast carcinoma
- Cellular location: Cytoplasm
Target Information
Cytokeratin 19 is part of a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40–68 kDa and isoelectric pH between 4.9–7.8.
Individual human cytokeratins are numbered 1 to 20. Expression patterns vary by epithelium type and differentiation degree, aiding in distinguishing epithelial malignancies.
Cytokeratin antibodies assist in differential tumor diagnosis via immunohistochemistry and are useful in cytopathology and flow cytometry.
Cytokeratin 19 is not expressed in hepatocytes, making it useful for identifying liver metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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