Thermo Fisher Scientific MMP3 Monoclonal Antibody (OTI3F11), TrueMAB
Human MMP3 단백질(aa 246-477)에 특이적인 Mouse monoclonal antibody. IHC(P) 1:150 희석으로 검증됨. Lyophilized 형태, PBS buffer(8% trehalose) 포함. 연구용으로 조직 재생, 단백질 분해 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 246–477 of human MMP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form and activated by extracellular proteinase cleavage. MMP3 binds zinc and calcium ions and exhibits metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin, playing roles in wound repair and tissue remodeling. Mutations in this gene may contribute to coronary heart disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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