Thermo Fisher Scientific RORB Polyclonal Antibody
RORβ 단백질을 인식하는 토끼 유래 폴리클로날 항체로, IHC(P) 등 다양한 연구용 분석에 적합함. 인간 및 여러 동물 종에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적 유지 가능.
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Thermo Fisher Scientific RORB Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Chicken, Horse, Hamster, Human, Mouse, Non-human primate, Sheep, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from hinge domain of human ROR Beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551515 |
Target Information
Retinoid-related orphan receptor beta (RORβ), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing.
Disruption of RORβ in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility.
RORβ binds to monomeric response elements containing the sequence AnnTAGGTCA as a monomer.
An alternatively spliced isoform, RORβ2, has been isolated from rats, and its expression is confined to the pineal gland and retina.
RORβ2 shares common DNA- and putative ligand-binding domains with wild-type RORβ but differs in the amino-terminal domain.
RORβ expression has been documented in various regions of the mouse brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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