Thermo Fisher Scientific CD229 Monoclonal Antibody (312830)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Flow Cytometry (Flow)

2.5 µg per million cells

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

312830

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse CD229/SLAMF3 Lys48-Phe454 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD229 (Ly9),uniProtId:Q01965-1,ncbiNodeId:10090,antigenRange:48-454,antigenLength:654,antigenImageFileName:MA5-24034_CD229_Ly9_Q01965-1_Rat.svg,antigenImageFileNamePDP:MA5-24034_CD229_Ly9_Q01965-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608164

Product Specific Information

In Western blots, no cross-reactivity with recombinant human CD229 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.