Thermo Fisher Scientific Claudin 19 Polyclonal Antibody
Claudin 19 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. ICC/IF에 사용 가능하며, Affinity chromatography로 정제되었습니다. PBS buffer(40% glycerol)로 보관되며, 연구용으로 적합합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 37–71). Recombinant protein control fragment: Product #RP-109977 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092015 |
Product Specific Information
- Immunogen sequence:
GDAIITAVGL YEGLWMSCAS QSTGQVQCKL YDSLL - Antigen sequence identity:
Mouse 100%; Rat 100%
Target Information
The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.
Defects in this gene cause hypomagnesemia renal with ocular involvement (HOMGO), a progressive renal disease characterized by primary renal magnesium wasting, hypomagnesemia, hypercalciuria, and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia, and nystagmus.
Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
[Provided by RefSeq, Jun 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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