Thermo Fisher Scientific IFI6 Polyclonal Antibody
Human IFI6 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공. PBS/glycerol buffer로 보관하며, 세포 생존 및 apoptosis 연구에 활용 가능.
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Thermo Fisher Scientific IFI6 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from C-terminal of human IFI6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635628 |
Product Specific Information
This antibody detects endogenous levels of total IFI6 protein.
Target Information
G1P3, also known as Interferon alpha-inducible protein 6 (IFI6) and Interferon-induced protein 6-16, is a 130 amino acid member of the IFI6 family of proteins.
Localized to the mitochondria, G1P3 is a multi-pass membrane protein induced by IFN-α2β.
It plays a major role in the apoptosis pathway, acting as a cell survival protein by inhibiting caspase-3 activity, which antagonizes apoptosis.
G1P3 has been implicated in tumorigenesis and is the subject of therapeutic studies, as reducing G1P3-mediated antiapoptotic signals could improve therapies for myeloma or other malignancies.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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