Thermo Fisher Scientific RAD23B Polyclonal Antibody
RAD23B 단백질을 검출하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from N-terminal of human RAD23B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2635621 |
Product Specific Information
The antibody detects endogenous levels of total RAD23B protein.
Target Information
The RAD23B gene encodes one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). RAD23B is part of a protein complex that complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts in vitro. It interacts with and enhances the activity of 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition during base excision repair. The protein contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, indicating involvement in ubiquitin-mediated proteolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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