Thermo Fisher Scientific ADAMTS4 Monoclonal Antibody (OTI6F1), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The ADAMTS4 gene encodes a member of the ADAMTS protein family, characterized by distinct modules such as a propeptide region, metalloproteinase domain, disintegrin-like domain, and thrombospondin type 1 motif.
This enzyme lacks a C-terminal TS motif and is involved in the degradation of aggrecan (a major cartilage proteoglycan) and brevican (a brain-specific extracellular matrix protein).
Such activity indicates its roles in arthritic disease and possibly in glioma progression within the central nervous system.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.