Thermo Fisher Scientific UBA52 Monoclonal Antibody (OTI5D12), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

Ubiquitin is a highly conserved protein involved in targeting cellular proteins for degradation via the 26S proteasome.
The UBA52 gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus.
When expressed in yeast, the protein is post-translationally processed to generate free ubiquitin monomer and ribosomal protein S27a.
Ribosomal protein S27a is a component of the 40S ribosomal subunit, belongs to the S27AE family, contains C4-type zinc finger domains, and is located in the cytoplasm.
Pseudogenes derived from this gene are present in the genome.
Similarly, ribosomal proteins L40 and S30 are synthesized as fusion proteins with ubiquitin or ubiquitin-like proteins.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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