Thermo Fisher Scientific TG Monoclonal Antibody (UMAB270), UltraMAB
인체 Thyroglobulin(TG)을 표적으로 하는 Mouse IgG1 단클론 항체로, IHC(P)에서 1:200 희석 비율로 검증됨. 무보존제, 동결건조 형태로 제공되며, 연구용으로만 사용 가능. 항체 재구성 및 결합 실험에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB270 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882)
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and biosynthesis of thyroid hormones (T4 and T3).
Autoantibodies against hTg are present in autoimmune thyroid diseases such as Hashimoto thyroiditis and Graves disease, with the highest levels observed in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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