Thermo Fisher Scientific TG Monoclonal Antibody (UMAB269), UltraMAB
Human TG 단백질을 인식하는 Mouse monoclonal antibody (Clone UMAB269). IHC(P)에서 검증됨. 고순도의 액상 형태로 제공되며, PBS/BSA/glycerol buffer에 보존. Thyroglobulin 관련 연구 및 자가면역성 갑상선 질환 연구에 적합.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:200 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB269 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Autoimmune thyroid disorders, such as Hashimoto thyroiditis and Graves disease, are associated with anti-thyroglobulin autoantibodies, which were the first discovered autoimmune factors.
Anti-hTG is highly expressed in Hashimoto thyroiditis and is also characteristic of thyroid cancer, making it useful for monitoring thyroid cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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