Thermo Fisher Scientific Phospho-C5AR1 (Ser334) Polyclonal Antibody
인간 C5AR1의 Ser334 인산화 부위를 인식하는 Rabbit Polyclonal 항체로 Western blot에 최적화됨. 비결합형 액상 형태이며 1 mg/mL 농도. C5aR1 관련 면역 반응 및 염증 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human C5R1 around the phosphorylation site of Ser334 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903234 |
Target Information
CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract.
CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, CD88 stimulates chemotaxis, granule enzyme release, and superoxide anion production.
CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and may be a component of the membrane attack complex.
Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지: PA5-118734_C5AR1_P21730-1_Rabbit.svg)
(이미지: PA5-118734_C5AR1_P21730-1_Rabbit_PDP.jpeg)
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