Thermo Fisher Scientific ARTS Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:15,000

-

Immunoprecipitation (IP)

10 µL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide, conjugated to KLH, corresponding to residues K-N(247) I Q D N R V H C C L Y F I S P F G H G(266) of human ARTS, with an N-terminal if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ARTS,uniProtId:O43236-1,ncbiNodeId:9606,antigenRange:247-266,antigenLength:478,antigenImageFileName:PA1-24694_ARTS_O43236-1_Rabbit.svg,antigenImageFileNamePDP:PA1-24694_ARTS_O43236-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

IgG fraction

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_779307

Product Specific Information

PA1-24694 is expected to cross react with mouse (100% conserved) due to sequence homology.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.