Thermo Fisher Scientific AKAP12 Polyclonal Antibody
AKAP12 단백질을 인식하는 Thermo Fisher Scientific의 sheep 유래 polyclonal 항체. Western blot 및 Immunoprecipitation에 적합하며 rat aortic smooth muscle을 양성 대조로 권장. 4°C 단기, -20°C 장기 보관 가능.
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Thermo Fisher Scientific AKAP12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–5 µg/mL |
| Immunoprecipitation (IP) | 2–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified, full length, native rat protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2225745 |
Product Specific Information
- Recommended positive control: rat aortic smooth muscle
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins that bind to the regulatory subunit of protein kinase A (PKA) and localize the holoenzyme to specific sites within the cell.
This gene encodes a member of the AKAP family expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells.
It associates with protein kinases A and C and phosphatase, serving as a scaffold protein in signal transduction.
AKAP12 and RII PKA colocalize at the cell periphery and are involved in cell growth regulation.
Antibodies to this protein can be produced by patients with myasthenia gravis.
Alternative splicing results in two transcript variants encoding different isoforms.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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