Thermo Fisher Scientific RelA Polyclonal Antibody
Goat에서 유래한 Polyclonal 항체로, NF-κB p65(RelA) 단백질을 인식합니다. Western blot과 Immunoprecipitation에 적합하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 501–551 of Human Reticuloendotheliosis Viral Oncogene Homolog A (NFκB p65, UniProt ID: Q04206-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Nuclear factor κB p65 (NF-κB p65), encoded by the RELA gene on human chromosome 11, is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A). It belongs to the Rel protein family and forms a heterodimer with p50 or p52 subunits of NF-κB. TNF-α binding to its receptor activates IKK, leading to IκB phosphorylation and degradation, thereby releasing NF-κB for transcriptional activation. NF-κB p65 plays a key role in regulating the transcription of the immunoglobulin κ (kappa) gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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