Thermo Fisher Scientific RelA Polyclonal Antibody
RelA(NF-κB p65) 단백질을 인식하는 Goat Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot과 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 501–551 of Human Reticuloendotheliosis Viral Oncogene Homolog A (NFkB p65, UniProt ID: Q04206-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene located on chromosome 11 in humans. Also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A), it belongs to the Rel family of proteins and forms a heterodimer with p50 or p52 subunits of NF-kB. Upon TNF-α binding to its receptor, IKK is phosphorylated, leading to phosphorylation and proteasomal degradation of IκB, allowing NF-kB to translocate to the nucleus. NF-kB p65 plays a key role in transcription of the immunoglobulin κ gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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