Thermo Fisher Scientific DAXX Monoclonal Antibody (PCRP-DAXX-8B7)
인간 DAXX 단백질을 인식하는 마우스 단클론 항체로, ICC/IF, 유세포분석, 펩타이드 어레이에 사용 가능. 고순도 Protein A/G 정제, PBS 버퍼 기반, 4°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific DAXX Monoclonal Antibody (PCRP-DAXX-8B7)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-DAXX-8B7 |
| Immunogen | Recombinant full-length human DAXX protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and cytoplasm. It interacts with various proteins such as apoptosis antigen Fas, centromere protein C, and transcription factor E26 oncogene homolog 1. In the nucleus, it acts as a transcription repressor binding to sumoylated transcription factors. Its repression can be relieved by sequestration into promyelocytic leukemia nuclear bodies or nucleoli. The protein associates with centromeres in G2 phase and may regulate apoptosis in the cytoplasm. Subcellular localization and function are modulated by post-translational modifications including sumoylation, phosphorylation, and polyubiquitination. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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