Thermo Fisher Scientific TNFR1 Monoclonal Antibody (943BC15C12), Biotin
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
AHR3819 | - | Thermo Fisher Scientific AHR3819 TNFR1 Monoclonal Antibody (943BC15C12), Biotin 100 ug pk | 재고문의 | pk | 647,000원 | - | 711,700원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
ELISA (ELISA)
Assay-dependent
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
943BC15C12
Immunogen
Recombinant human sTNF-RI.
Conjugate
Biotin Biotin Biotin
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.5, with 5mg/mL BSA
Contains
0.5mg/mL sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2536358
Product Specific Information
This product is recommended as a detection antibody in Sandwich ELISA applications.
This clone can also be referred to as clone number 943BC 15C12 2D6.
Target Information
TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors. TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression. The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1). In humans, the TNFR1 gene is located on chromosome 12. Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of TNFR1 were found to be associated with the autosomal dominant periodic fever syndrome, and the impaired receptor clearance is thought to be a mechanism of the disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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