Thermo Fisher Scientific CD181 (CXCR1) Monoclonal Antibody (501)
CXCR1 단백질을 표적으로 하는 mouse IgG1 단클론 항체로, Western blot, IHC, ICC, Flow cytometry 등 다양한 연구용 응용에 사용 가능. 인간 시료에 검증됨. 액상 형태로 제공되며 -20°C에서 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 501 |
| Immunogen | A 14 amino acid peptide corresponding to aa 5–19 at the N-terminus of human CXCR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Wet or Dry ice (international) |
| RRID | AB_2536356 |
Target Information
CXCR1 is a member of the G-protein-coupled receptor family and acts as a receptor for interleukin 8 (IL8). It binds IL8 with high affinity and transduces the signal via a G-protein activated second messenger system. Knockout studies in mice suggest that CXCR1 inhibits embryonic oligodendrocyte precursor migration in the developing spinal cord.
This gene, IL8RB (encoding another high-affinity IL8 receptor), and IL8RBP (a pseudogene of IL8RB) form a gene cluster located on chromosome 2q33–q36.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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