Thermo Fisher Scientific CD1b/CD1c Monoclonal Antibody (B-B5), FITC

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Flow Cytometry (Flow)

Assay-dependent

View 3 publications 3 publications

Miscellaneous PubMed (Misc)

-

View 2 publications 2 publications

Product Specifications

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

B-B5

Immunogen

Thymus cells, Jurkat (T cell line) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD1b/CD1c,uniProtId:P29016-1,ncbiNodeId:9606,antigenRange:1-333,antigenLength:333,antigenImageFileName:AHS0198_CD1bCD1c_P29016-1_House_mouse.svg,antigenImageFileNamePDP:AHS0198_CD1bCD1c_P29016-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:CD1b/CD1c,uniProtId:P29017-1,ncbiNodeId:9606,antigenRange:1-333,antigenLength:333,antigenImageFileName:AHS0198_CD1bCD1c_P29017-1_House_mouse.svg,antigenImageFileNamePDP:AHS0198_CD1bCD1c_P29017-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra

Form

Liquid

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2536362

Target Information

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.