Thermo Fisher Scientific alpha-ENaC Monoclonal Antibody (2G4), APC
Thermo Fisher Scientific의 alpha-ENaC Monoclonal Antibody (2G4), APC는 쥐 및 랫트 시료에서 ENaC α 단백질 검출에 적합한 단클론 항체입니다. APC 형광 표지로 세포 분석에 활용 가능하며, WB 및 IHC에 최적화되어 있습니다. 단백질 G로 정제된 고순도 항체로 4°C에서 보관합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific alpha-ENaC Monoclonal Antibody (2G4), APC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:150 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G4 |
| Immunogen | Synthetic peptide from the N-terminal of Rat ENaC alpha (aa. 46–68) |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931803 |
Additional Formats Available
- FITC (Cat. No. MA5-45350)
- PerCP (Cat. No. MA5-45351)
- Custom conjugation available upon request
Product Specific Information
A 1:1,000 dilution of MA5-45349 was sufficient for detection of ENaC alpha in 15 µg of mouse whole kidney lysate by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 85 kDa.
Target Information
Epithelial sodium channels (ENaC) are amiloride-sensitive members of the Deg/ENaC superfamily of ion channels. These channels share a common structure with two intracellular termini, two transmembrane domains, and a large extracellular loop containing conserved cysteine residues.
ENaC has three homologous isoforms: alpha, beta, and gamma. It plays a crucial role in sodium and fluid balance in tissues such as the kidney, lung, and colon. ENaC activity is regulated by aldosterone and is involved in blood pressure control.
Mutations in ENaC subunits are associated with disorders such as Liddle’s syndrome (hypertension) and pseudohypoaldosteronism type 1 (PHA-1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.