Thermo Fisher Scientific GDF15 Polyclonal Antibody
GDF15 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, Human 및 비인간 영장류 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding Tyr60 of human Mic-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 182 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981320 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
GDF-15 belongs to the TGF-beta cytokine family, which plays an important role during prenatal development, postnatal growth, and tissue remodeling. GDF-15 is mainly expressed in the placenta and at lower levels in other tissues. Its presence in amniotic fluid and elevated serum levels in pregnant women suggest involvement in gestation and embryonic development. GDF-15 generally exhibits tumor-suppressive activity and is produced in response to p53 pathway activation. Serum GDF-15 levels are positively correlated with progression of several tumor types, including colorectal, pancreatic, and prostate cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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