Thermo Fisher Scientific GDF15 Polyclonal Antibody
GDF15 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot에 적합합니다. Human 및 비인간 영장류 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the carboxyl terminus of human Mic-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980095 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
GDF-15 belongs to the TGF-beta cytokine family, which plays an important role during prenatal development, postnatal growth, and tissue remodeling. It is expressed predominantly in the placenta and, to a lesser extent, in other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest its involvement in gestation and embryonic development. GDF-15 generally exhibits tumor suppressive activity and is a major factor produced in response to activation of the p53 pathway. Serum levels of GDF-15 are positively correlated with neoplastic progression in several tumor types, including colorectal, pancreatic, and prostate cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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