Thermo Fisher Scientific Phospho-NDRG1 (Thr346) Polyclonal Antibody
인산화 NDRG1(Thr346)을 인식하는 Rabbit Polyclonal 항체로 인간, 생쥐, 랫트에 반응합니다. Western blot 및 Immunoprecipitation에 적합하며, Protein A로 정제된 액상 형태입니다. 보존제 없이 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: View 1 publication
Immunoprecipitation (IP)
- Tested Dilution: 1:100
- Publications: None listed
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pThr346 of NDRG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 6 µg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984103 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
NDRG1 is a 394-amino-acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth, and differentiation.
Defects in NDRG1 cause Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet.
NDRG1 plays a growth inhibitory role and serves as a marker of differentiation. It is expressed in placental membranes, prostate, kidney, small intestine, ovary, colon, and the cells bordering the lumen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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