Thermo Fisher Scientific Phospho-Kinesin 5B (Ser154) Polyclonal Antibody
Kinesin 5B의 Ser154 인산화 부위를 인식하는 폴리클로날 항체로, Western blot에 적합합니다. 사람, 생쥐, 랫트 반응성이 있으며, PBS/glycerol buffer에 보존됩니다. 순도 높은 액상 항체로 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5105705
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KIF5B (Accession P33176), corresponding to amino acid residues around phosphorylated Ser154 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817133 |
Product Specific Information
This antibody detects endogenous levels of KIF5B only when phosphorylated at Ser154.
Target Information
Kinesin 5B is a microtubule-dependent motor protein required for the normal distribution of mitochondria and lysosomes. It can induce the formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. It regulates centrosome and nuclear positioning during mitotic entry, antagonizing dynein function and driving the separation of nuclei and centrosomes in a BICD2-dependent manner during the G2 phase. It is also required for anterograde axonal transportation of MAPK8IP3/JIP3, which is essential for axon elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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