Thermo Fisher Scientific N-WASP Polyclonal Antibody
N-WASP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화됨. Human 및 Mouse 시료에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며, 세포골격 관련 연구에 적합.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human WASL (Accession O00401), corresponding to amino acid residues E231–P281 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853898 |
Product Specific Information
Antibody detects endogenous levels of total N-WASP.
Target Information
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structures and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. These proteins are regulated by various stimuli and interact with multiple partners.
Recent studies show that WAS family proteins associate with the small GTPase Cdc42, which regulates actin filament formation and the cytoskeletal organizing complex Arp2/3.
The WASL gene product, a homolog of WAS protein, is ubiquitously expressed with highest levels in neural tissues. It binds directly to Cdc42 and induces the formation of long actin microspikes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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