
Thermo Fisher Scientific NEK2 Polyclonal Antibody
NEK2 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, 인간 및 랫트 시료에 반응합니다. Western blot에 적합하며, 세포주기 조절 및 염색체 분리 연구에 활용됩니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NEK2 (Accession P51955), corresponding to amino acid residues N146–K196 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853902 |
Product Specific Information
Antibody detects endogenous levels of total NEK2.
Target Information
NEK2 is a serine/threonine-protein kinase involved in cell cycle regulation and essential for faithful chromosome segregation. It is primarily located in the centrosome and plays a crucial role in mitosis regulation. During the G1 phase, NEK2 is undetectable, but its levels progressively increase throughout the S phase, peaking in late G2 phase. The gene has several alternatively spliced transcript variants that encode different isoforms with distinct C-termini. NEK2 is associated with diseases such as Retinitis Pigmentosa 67 and Retinitis Pigmentosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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