Thermo Fisher Scientific PRKG2 Monoclonal Antibody (OTI10D5), TrueMAB
Human PRKG2 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 연구용으로만 사용되며, PRKG2 관련 신호전달 연구에 유용합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 40–320 of human PRKG2 (NP_006250) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PRKG2 (PKG2, cGKII) is a cAMP- and cGMP-dependent protein kinase involved in various cellular functions.
cGKII plays a key role in physiological pathways such as intestinal secretion of water and electrolytes induced by E. coli toxin STa and guanylin.
It also acts as a molecular switch regulating chondrocyte differentiation by attenuating SOX9 function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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