Thermo Fisher Scientific GAB2 Polyclonal Antibody
GAB2 단백질을 검출하기 위한 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot 및 IHC(P) 실험에 최적화. 인간, 마우스, 랫트 반응성. 고순도 affinity chromatography 정제 및 안정적 PBS/glycerol buffer 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GAB2 (Accession Q9UQC2), corresponding to amino acid residues Q588–D638 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818091 |
Product Specific Information
Antibody detects endogenous levels of total Gab2.
Target Information
This gene belongs to the GRB2-associated binding protein (GAB) family. These proteins contain pleckstrin homology (PH) domains and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters transmitting signals in response to cytokine and growth factor receptor stimulation, as well as T- and B-cell antigen receptor activation. The encoded protein is a principal activator of phosphatidylinositol-3 kinase in response to high-affinity IgE receptor activation. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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