Thermo Fisher Scientific Collagen II Polyclonal Antibody
Collagen II 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에 반응합니다. WB, IHC, ICC 등 다양한 응용에 사용 가능하며, 고순도 Affinity chromatography 정제 제품입니다. 연구용으로 -20°C 보관하며 안정적인 신호 검출을 제공합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COL2A1 (Accession P02458), corresponding to amino acid residues K113–P163 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818092 |
Product Specific Information
Antibody detects endogenous levels of total Collagen II.
Target Information
COL2A1 encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye.
Mutations in this gene are associated with various skeletal disorders, including:
- Achondrogenesis
- Chondrodysplasia
- Early onset familial osteoarthritis
- SED congenita
- Langer-Saldino achondrogenesis
- Kniest dysplasia
- Stickler syndrome type I
- Spondyloepimetaphyseal dysplasia Strudwick type
Defects in processing chondrocalcin, a calcium-binding protein that is the C-propeptide of this collagen molecule, are also linked to chondrodysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-99159_Collagen_II_P02458-2_Rabbit.svg 및 PA5-99159_Collagen_II_P02458-2_Rabbit_PDP.jpeg)
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