Thermo Fisher Scientific Calbindin D28K Monoclonal Antibody (5A9)
Calbindin D28K 단백질을 특이적으로 인식하는 Mouse Monoclonal 항체. Western blot 및 IHC(Paraffin) 검증 완료. 다양한 종(Bovine, Human, Mouse)에 반응. Protein G 정제 및 PBS/glycerol buffer에 보관. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A9 |
| Immunogen | Recombinant full length human calbindin purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 5 mM sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942666 |
Product Specific Information
Specific for endogenous levels of the ~28 kDa calbindin protein.
Target Information
Calbindin-D-28K (also known as vitamin D-dependent calcium-binding protein or cholecalcin) is a highly conserved 28 kDa calcium-binding protein with broad tissue distribution. It belongs to a family of low molecular weight calcium-binding proteins (CaBPs) such as calmodulin, S-100, parvalbumin, and troponin C. These CaBPs share homologous EF-hand type polypeptide folds for Ca²⁺ binding.
Calbindin-D-28K is predominantly found in subpopulations of neurons in the central and peripheral nervous systems and in epithelial cells involved in Ca²⁺ transport, such as distal tubular and cortical collecting tubule cells of the kidney, as well as enteric neuroendocrine cells.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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