Thermo Fisher Scientific CGRP Monoclonal Antibody (4901)
Rat alpha-CGRP에 특이적인 단클론 항체로 ICC/IF에 적합. Rat, human CGRP를 인식하며 높은 특이성과 재현성을 제공. Protein G 정제, 액상 형태로 안정적 보관 가능. 연구용으로만 사용.
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Thermo Fisher Scientific CGRP Monoclonal Antibody (Clone 4901)
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4901 |
| Immunogen | Purified rat alpha-CGRP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 10 mM HEPES, pH 7.5, with 100 µg/mL BSA, 50% glycerol, 150 mM NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942668 |
Product Specific Information
This antibody is specific for Calcitonin Gene Related Peptide (CGRP).
It also recognizes rat beta-CGRP and human alpha-CGRP (10-fold less sensitivity compared to rat alpha-CGRP).
Suggested positive controls include dorsal root ganglia, pancreas, and gut.
Target Information
This gene encodes peptide hormones including calcitonin, calcitonin gene-related peptide, and katacalcin through tissue-specific alternative RNA splicing and cleavage of inactive precursor proteins.
Calcitonin regulates calcium and phosphorus metabolism, CGRP functions as a vasodilator, and katacalcin acts as a calcium-lowering peptide.
Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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