Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI3F3), TrueMAB
인간 KLK8 단백질을 인식하는 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 암 및 질환 바이오마커 연구용으로 적합.
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Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI3F3), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological roles. Many kallikreins are implicated in carcinogenesis and may serve as novel biomarkers for cancer and other diseases.
The KLK8 gene is one of fifteen kallikrein subfamily members located in tandem on chromosome 19. The encoded protein may participate in proteolytic cascades in the skin and act as a biomarker for ovarian cancer.
Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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