Thermo Fisher Scientific RASGRP3 Monoclonal Antibody (OTI2G7), TrueMAB
RASGRP3 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 검증 완료. 인간 시료 반응성. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 적합. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 380–690 of human RASGRP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Members of the RAS subfamily of GTPases function as molecular switches cycling between inactive GDP-bound and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, act as RAS activators by promoting GTP acquisition, linking cell surface receptor signaling to RAS activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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