Thermo Fisher Scientific SLC16A2 Polyclonal Antibody
SLC16A2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간, 마우스, 랫트 시료에 반응하며, Affinity chromatography로 정제됨. 세포 내 SLC16A2 단백질 수준 검출에 적합.
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- PA5101676
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC16A2 (Accession P36021), corresponding to amino acid residues N111–V161 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851110 |
Product Specific Information
This antibody detects endogenous levels of total SLC16A2.
Target Information
Monocarboxylates such as lactate and pyruvate are key components of cellular metabolism. Lactic acid, produced during glycolysis, must be exported from the cell to maintain pH balance and sustain ATP production. This transport is mediated by the monocarboxylate transporter (MCT) family, which functions as proton symports selective for L-lactate. The MCT family includes at least eight members (MCT1–8), each containing 10–12 transmembrane domains with cytoplasmic N- and C-termini. Mutations in the SLC16A2 gene, encoding MCT8, can cause monocarboxylate transporter 8 deficiency (MCT8 deficiency), an X-linked disorder associated with impaired hormone transport, psychomotor retardation, and abnormal thyroid levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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