Thermo Fisher Scientific MRP7 Polyclonal Antibody
Thermo Fisher Scientific의 MRP7 Polyclonal Antibody는 인간 MRP7 단백질을 특이적으로 인식하는 토끼 IgG 항체입니다. Western blot 및 Immunocytochemistry에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 버퍼에 보존되어 안정적이며 연구용으로 사용 가능합니다.
- 카탈로그번호
- PA5101678
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: View 2 publications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ABCC10 (Accession Q5T3U5), corresponding to amino acid residues A1351–K1401 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851112 |
Product Specific Information
Antibody detects endogenous levels of total MRP7.
Target Information
The MRP family consists of nine similar ABC transporters that transport structurally diverse lipophilic anions and function as efflux pumps.
MRP7 (multidrug resistance-associated protein 7, ATP-binding cassette sub-family C member 10) is a multi-pass membrane protein in the ABC transporter family.
It mediates ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG) and contributes to cellular detoxification through lipophilic anion extrusion.
MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains.
Three isoforms are known: isoform 2 is widely expressed, while isoform 1 is predominantly expressed in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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