Thermo Fisher Scientific Collagen I/III Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Frozen) (IHC (F))

1:10-1:40

-

Immunocytochemistry (ICC/IF)

1:10-1:40

-

ELISA (ELISA)

1:500-1:2,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Porcine collagen, types 1 and 3 from skin.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.1 mg/mL

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_930074

Product Specific Information

This antibody shows <0.5% cross-reactivity with porcine albumin and immunoglobulins.

Reconstitute with 0.5 mL of distilled water or saline. Prior to reconstitution, store at 4ºC. After reconstitution, store undiluted at -20ºC, avoiding freeze/thaw cycles.

Rabbit anti Porcine collagen I/III antibody reacts with native and heat denatured porcine collagen type 1 and 3.Less than 0.5% reactivity is observed with porcine albumin and immunoglobulins.

Target Information

Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.