Thermo Fisher Scientific Influenza A HA Recombinant Human Monoclonal Antibody (CR6261)

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Neutralization (Neu)

Assay-dependent

-

Functional Assay (Functional)

Assay-dependent

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Human / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

CR6261

Immunogen

The original antibody was isolated using phage display from the IgM+ memory B cells of a healthy individual vaccinated against influenza.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

This antibody binds hemaglutinin of most group 1 influenza viruses. CR6261 recognizes a highly conserved helical region in the membrane-proximal stem of HA1/HA2.

Target Information

Infectious diseases are the leading cause of death worldwide. AIDS, tuberculosis (TB), malaria, diarrhoeal and respiratory infections account for 78% of deaths caused by infectious disease. As many infectious diseases are controlled, new diseases emerge and old diseases become resistant to current drugs. Many infectious diseases have been associated with an increase risk of carcinoma. Influenza continues to attract researchers as new strains appear by the ability of the influenza gene to mix with different forms of the virus. Recently, research on SARS and West Nile virus has risen due to the increased number of infections. These antibodies assist in research by detecting the infectious disease agent.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.