Thermo Fisher Scientific CD82 Monoclonal Antibody (B-L2)
CD82 단백질을 인식하는 Mouse monoclonal antibody(B-L2 clone). 인간 시료에 반응하며 IHC(F), ICC/IF, Flow Cytometry에 적합. 액상 형태로 제공되며 PBS 및 1% BSA buffer에 보관. 종양 진행 관련 연구에 유용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B-L2 |
| Immunogen | CD82 transfected murine mastocytoma cell line P815 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.025 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745102 |
Target Information
This metastasis suppressor gene product is a membrane glycoprotein that belongs to the transmembrane 4 superfamily. Expression of this gene is downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and loss of both proteins is associated with poor survival in prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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