Thermo Fisher Scientific CD104 (Integrin beta 4) Monoclonal Antibody (450-9D), FITC
CD104 (Integrin beta 4) 단백질을 인식하는 FITC 결합 단클론 항체로, 인간 시료에 반응합니다. ICC/IF 및 유세포분석(Flow Cytometry)에 사용 가능하며, 단백질 G로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 450-9D |
| Immunogen | Purified alpha6 beta4 integrin from A431 cells |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745100 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope on the CD104 molecule.
Target Information
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities.
Integrins mediate cell-matrix or cell-cell adhesion, and transduce signals that regulate gene expression and cell growth.
This gene encodes the integrin beta 4 subunit, a receptor for the laminins. The subunit tends to associate with the alpha 6 subunit and plays a pivotal role in the biology of invasive carcinoma.
Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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