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Thermo Fisher Scientific PKN2 Monoclonal Antibody (1D1)
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PRK2 단백질을 검출하기 위한 Mouse IgG1 단일클론 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 등 반응성. 액상 형태로 4°C 단기, -20°C 장기 보관 가능. 연구용 전용 제품.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 28. 오전 12:38
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Thermo Fisher Scientific MA515887 PKN2 Monoclonal Antibody (1D1) 100 ul pk판매 단위 pk ·
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755,700원VAT 포함 831,270원
Thermo Fisher Scientific · Thermo Fisher Scientific PKN2 Monoclonal Antibody (1D1)
Thermo Fisher Scientific PKN2 Monoclonal Antibody (1D1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D1 |
| Immunogen | Purified recombinant fragment of human PRK2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C for short term; -20°C for long term. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155620 |
Product Specific Information
MA5-15887 targets PRK2 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human, Mouse, Non-human primate, and Rat samples.
The immunogen is a purified recombinant fragment of human PRK2 expressed in E. coli.
MA5-15887 detects PRK2 with a predicted molecular weight of approximately 140 kDa.
Target Information
PKN2 (PRK2), a close relative of PKCs, is a regulator of mitosis and cytokinesis exit. It plays a role in:
- Cell cycle progression regulation (G2/M phase)
- Actin cytoskeleton assembly and cell migration
- Cell adhesion and tumor cell invasion
- Transcription activation signaling
- Phosphorylation of CTTN and HDAC5, affecting actin association and nuclear import
- RhoA-mediated apical junction formation in epithelial cells
- FYN kinase activation for keratinocyte differentiation
- Inhibition of Akt pro-survival signaling
- Stimulation of HCV RNA replication via NS5B phosphorylation
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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