Thermo Fisher Scientific ECM1 Monoclonal Antibody (SC-05)
ECM1 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot, IHC, IP 등 다양한 응용에 사용 가능. Human에 반응하며, Protein A로 정제된 1 mg/mL 액상형 제품. ECM1 관련 질환 연구 및 암 조직 표지에 유용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 2–8 µg/mL | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SC-05 |
| Immunogen | Affinity-purified secretory component from human colostrum |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2095636 |
Product Specific Information
This antibody reacts with 80 kDa human secretory component glycoprotein (both free and bound in secretory IgA). The recognized glycoprotein is a specific membrane marker of glandular carcinomas.
Target Information
ECM1 (Extracellular Matrix Protein 1) is a protein involved in extracellular matrix organization and cell adhesion. It is expressed in various tissues such as skin, lung, and liver, and plays roles in development, angiogenesis, and tumor biology. ECM1 interacts with collagen and fibronectin, influencing cell proliferation, migration, and invasion. Mutations in ECM1 are linked to lipoid proteinosis (Urbach-Wiethe disease) and lichen sclerosus et atrophicus. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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