
Thermo Fisher Scientific CEA Recombinant Rabbit Monoclonal Antibody (061), FITC
FITC로 표지된 재조합 토끼 단클론 항-CEA 항체. 인간 CEA(CEACAM5)에 특이적이며 유세포분석(Flow Cytometry)에 적합. Protein A 정제, PBS/0.5% BSA 보존액, 4°C 암소 보관. 연구용으로만 사용.
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Applications
- Flow Cytometry (Flow): 5 µL/test
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 061 |
| Immunogen | Recombinant protein encoding Human CEA (Met1–Ala685) |
| Conjugate | FITC |
| Excitation/Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.5% BSA |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2937794 |
Additional Formats
- Unconjugated (MA5-36005)
- APC (MA5-46721)
- PE (MA5-46723)
- Custom conjugation available upon request
Product Specific Information
Preparation:
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD66e (CEACAM5) (Met1–Ala685) and conjugated with FITC under optimum conditions; unreacted FITC was removed.
Storage:
This antibody can be stored at 2–8°C for twelve months without detectable loss of activity. Protect from prolonged exposure to light. Do not freeze.
Target Information
CEA (Carcinoembryonic Antigen, CD66e) is synthesized during fetal gut development and re-expressed in increased amounts in intestinal carcinomas and other tumors.
CEA belongs to the immunoglobulin supergene family, consisting of one N domain and six constant-like domains (A1–A3, B1–B3).
Antibodies to CEA are useful for identifying the origin of metastatic adenocarcinomas and distinguishing pulmonary adenocarcinomas (60–70% CEA+) from pleural mesotheliomas (rarely or weakly CEA+).
CEA functions as a cell adhesion molecule and has roles in tissue differentiation, angiogenesis, apoptosis, tumor suppression, metastasis, and immune modulation.
Multiple transcript variants encoding different isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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