Thermo Fisher Scientific CRB1 Polyclonal Antibody
CRB1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. IHC(P) 실험에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CRB1. Recombinant protein control fragment (Product # RP-107048) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663090 |
Product Specific Information
Immunogen sequence:
LLLALENSTYQ YIRVWLERGR LAMLTPNSPK LVVKFVLNDG NVHLISLKIK PYKIELYQSS QNLGFISAST WKIEKGDV
Highest antigen sequence identity to the following orthologs:
- Mouse: 75%
- Rat: 68%
Target Information
CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa (RP12) and with Leber congenital amaurosis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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