Thermo Fisher Scientific CRB1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human CRB1. Recombinant protein control fragment (Product #RP-107048). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CRB1,uniProtId:P82279-1,ncbiNodeId:9606,antigenRange:751-829,antigenLength:1406,antigenImageFileName:PA5-66373_CRB1_P82279-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66373_CRB1_P82279-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.20 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663090

Product Specific Information

Immunogen sequence: LLLALENSTYQ YIRVWLERGR LAMLTPNSPK LVVKFVLNDG NVHLISLKIK PYKIELYQSS QNLGFISAST WKIEKGDV

Highest antigen sequence identity to the following orthologs - mouse 75%, rat 68%.

Target Information

CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.