Thermo Fisher Scientific APBA1 Polyclonal Antibody
APBA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제됨. 장기보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MINT1 (Product #RP-107049) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2663141 |
Product Specific Information
Immunogen sequence:
ALPNHLHFHSL EHEEAMNAAY SGYVYTHRLF HRGEDEPYSE PYADYGGLQE HVYEEIGDAP ELDARDGLRL YEQERDE
- Highest antigen sequence identity to the following orthologs: mouse 95%, rat 95%.
Target Information
The munc-18 interacting protein (Mint) family consists of conserved adaptor proteins involved in membrane transport and organization.
Mammals have three isoforms: Mint1, Mint2, and Mint3.
- Mint1 and Mint2: Expressed mainly in the brain; interact with Munc18, a key component of synaptic vesicle fusion.
- Mint3: Expressed ubiquitously, lowest in brain and testis; interacts with APP (amyloid precursor protein) via PTB and PDZ domains.
Mint3 may link APP to transport machinery, influencing its endocytosis and metabolism.
Abnormal APP metabolism is associated with early-onset Alzheimer’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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