Thermo Fisher Scientific Phospho-STAT2 (Tyr690) Polyclonal Antibody
STAT2 단백질의 Tyr690 인산화를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot과 ELISA에 적합하며, Human, Mouse, Rat 시료에서 반응. PBS/glycerol buffer에 보존되어 안정적이며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:500 | View 1 publication |
| ELISA | 1 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around Y690 of human STAT2 (NP_005410.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.05 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2809163 |
Product Specific Information
- Positive Samples: HeLa
- Cellular Location: Cytoplasm, Nucleus
- Immunogen Sequence: RRKYLK
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and then form homo- or heterodimers that translocate to the nucleus, where they act as transcription activators.
In response to interferon (IFN), STAT2 forms a complex with STAT1 and IFN regulatory factor p48 (ISGF3G), acting as a transactivator but lacking direct DNA-binding ability. Transcription adaptor P300/CBP (EP300/CREBBP) interacts specifically with STAT2 and is thought to be involved in blocking the IFN-alpha response by adenovirus.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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