Thermo Fisher Scientific PRDM14 Polyclonal Antibody
PRDM14 단백질을 인식하는 Rabbit polyclonal 항체로, Western blot, IHC, ELISA, ChIP 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 핵 내 PRDM14 단백질 검출에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| ChIP assay (ChIP) | 5 µg antibody for 10–15 µg of Chromatin |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–260 of human PRDM14 (NP_078780.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.12 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914495 |
Product Specific Information
Positive test controls include: NCI-H125, Mouse ovary, Rat lung.
The target is typically localized in the nucleus.
Immunogen sequence:
MALPRPSEAV PQDKVCYPPE SSPQNLAAYY TPFPSYGHYR NSLATVEEDF QPFRQLEAAA SAAPAMPPFP FRMAPPLLSP GLGLQREPLY DLPWYSKLPP WYPIPHVPRE VPPFLSSSHE YAGASSEDLG HQIIGGDNES GPCCGPDTLI PPPPADASLL PEGLRTSQLL PCSPSKQSED GPKPSNQEGK SPARFQFTEE DLHFVLYGVT PSLEHPASLH HAISGLLVPP DSSGSDSLPQ TLDKDSLQLP EGLCLMQTVF
Target Information
PRDM14 encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators.
This protein may exhibit histone methyltransferase activity and plays a critical role in maintaining cell pluripotency by repressing differentiation marker genes.
Its expression may also be associated with breast cancer.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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