Thermo Fisher Scientific SQSTM1 Polyclonal Antibody
SQSTM1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 반응성 확인. KLH 결합 합성 펩타이드(aa 317-346)를 면역원으로 제작. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 317–346 amino acids of human SQSTM1 (p62) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2196012 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
The SQSTM1 gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway. It functions as a scaffolding/adaptor protein with TNF receptor-associated factor 6 to mediate NF-κB activation in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified. Mutations in this gene are associated with sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-12092_SQSTM1_Q13501-1_Rabbit.svg, PA5-12092_SQSTM1_Q13501-1_Rabbit_PDP.jpeg)
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