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Thermo Fisher Scientific Phospho-TPL2 (Thr290) Polyclonal Antibody
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Phospho-TPL2 (Thr290)에 특이적인 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응. WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 제품으로, 세포 신호전달 연구에 적합.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 01. 오후 11:38
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Thermo Fisher Scientific PA536635 Phospho-TPL2 (Thr290) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
698,000원VAT 포함 767,800원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-TPL2 (Thr290) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: Not specified
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- View publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human Cot around the phosphorylation site of Threonine 290 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553627 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 53 kDa.
- Purity >95% by SDS-PAGE.
Target Information
MAP3K8 (COT) is a serine/threonine kinase that activates both MAP and JNK kinase pathways and plays a role in the cell cycle.
MAPK signaling cascades include MAPK (ERK), MAPK kinase (MEK), and MAPK kinase kinase (MEKK).
MEKK8 activates NF-kappa-B1 by stimulating proteasome-mediated proteolysis of NF-kappa-B1/p105.
Expressed in normal tissues and tumor-derived cell lines. The 58 kDa form is activated during S and G2/M phases of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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