Thermo Fisher Scientific TMEM16B Polyclonal Antibody
TMEM16B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. WB, ICC/IF, ELISA에 사용 가능. 고순도 Affinity Chromatography 정제, 액상 형태로 -20°C 보관.
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카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–200 of human ANO2 (NP_0012655261) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.28 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806363 |
Product Specific Information
Immunogen sequence:
MPEDIPLLPG SPRRLSPQAG SRGGQGPKHG QQCLKMPGPR APGLQGGSNR DPGQPCGGES TRSSSVINNY LDANEPVSLE ARLSRMHFHD SQRKVDYVLA YHYRKRGVHL AQGFPGHSLA IVSNGETGKE PHAGGPGDIE LGPLDALEEE RKEQREEFEH NLMEAGLELE KDLENKSQGS IFVRIHAPWQ VLAREAEFLK
Positive Samples: Mouse brain
Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCCs include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCCs but has different biophysical characteristics such as voltage dependence and unitary conductance.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-92044_TMEM16B_Q9NQ90-1_Rabbit.svg, PA5-92044_TMEM16B_Q9NQ90-1_Rabbit_PDP.jpeg)
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